Interactions of alginate-producing and -deficient Pseudomonas aeruginosa with zwitterionic polymers

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题名:	Interactions of alginate-producing and -deficient Pseudomonas aeruginosa with zwitterionic polymers
作者:	黃俊仁;Huang, Chun-Jen;Mi, Luo;Jiang, Shaoyi
贡献者:	工學院化學工程與材料工程學系
关键词:	Acrylamides - chemistry;adhesion;Advanced Basic Science;Alginates;bacteria;Bacterial Adhesion;Biocompatible Materials - chemistry;cations;Dentistry;environmental factors;exopolysaccharides;Glucuronic Acid - biosynthesis;Hexuronic Acids;Long-range surface plasmon resonance;Materials Testing;monitoring;Nonfouling properties;polymers;Polymers - chemistry;Polysaccharide;proteins;Pseudomonas aeruginosa;Pseudomonas aeruginosa - metabolism;Pseudomonas aeruginosa - physiology;Surface Plasmon Resonance;Surface Properties;Zwitterionic polymers;zwitterions
日期:	2012-05-01
上传时间:	2026-04-21 13:55:16 (UTC+8)
出版者:	Elsevier BV;Netherlands: Elsevier Ltd
摘要:	摘要： In this work, we report a study of the interactions between bacteria and zwitterionic polymers using a long-range surface plasmon resonance (LR-SPR) sensor. The LR-SPR with an extended probing field allows one to perform in-situ monitoring of bacterial adhesion and to investigate bacteria–surface interactions under various conditions. Alginate-producing and -deficient Pseudomonas aeruginosa were used in order to study the role of capsular exopolysaccharide in bacterial adhesion onto a surface. Polycarboxybetaine polymers with one and two carbons in spaces between two oppositely charged moieties on polymer side chains (pCBAA-1 and pCBAA-2) were prepared in order to unveil the effects of material properties on surface resistance to bacterial adhesion. In addition, environmental factors (e.g., divalent cations) were investigated. This work demonstrates the role of polysaccharides beyond proteins in bacteria adhesion and the effective resistance of pCBAA-1 against bacterial adhesion. 其他題名： Biomaterials 出版者： Netherlands: Elsevier Ltd 出版日期： 2012-05-01 出處： Biomaterials, 2012-05, Vol.33 (14), p.3626-3631 版權： 2012 Elsevier Ltd 版權： Elsevier Ltd 版權： Copyright Â© 2012 Elsevier Ltd. All rights reserved. 識別號： ISSN: 0142-9612 識別號： ISSN: 1878-5905 識別號： EISSN: 1878-5905 識別號： DOI: 10.1016/j.biomaterials.2012.01.059 識別號： PMID: 22349288
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