Microwave assistance of labeling hippuric acid by I-131

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题名:	Microwave assistance of labeling hippuric acid by I-131
作者:	謝發坤;Sherlock Huang, Lin-Chiang;Wu, Kou-Hung;Ko, Pi-Wen;Hsieh, Cheng-Ying;Pao, Kuan-Chuan;Chou, Shih-Ching;Shieh, Fa-Kuen;Sureshbabu, Radhakrishnan;Hsu, Ming-Hua
贡献者:	理學院化學學系
关键词:	Catalysis;Copper(II) acetate;Hippuric acid;I131 labeling;Iodine Radioisotopes - chemistry;Iodohippuric Acid - chemistry;Isotope Labeling - methods;Microwave;Microwaves;Organometallic Compounds - chemistry;Radiochemical purity;Radiopharmaceuticals - chemical synthesis
日期:	2014-07-01
上传时间:	2026-04-21 14:27:02 (UTC+8)
出版者:	England: Elsevier Ltd
摘要:	摘要： This work presents a novel approach for labeling hippuric acid with I-131 using microwaves. It utilizes copper(II) acetate as a catalyst of the labeling. The process involves the use of this catalytic copper(II) acetate at low dilutions that were nevertheless sufficient to produce labeled hippuric acid with high radiochemical purity in a short time. Therefore, the novel technique overcomes the limitations of previously reported conventional methods that involve heating. •We report the microwave assisted radiochemical labeling of hippuric acid by I-131.•Cu(OAc)2 can be used as catalyst to get labeled product in lower dilution condition.•Advantages of our method are lesser time scale and high radiochemical purity. [Display omitted] 其他題名： Appl Radiat Isot 出版者： England: Elsevier Ltd 出版日期： 2014-07-01 出處： Applied radiation and isotopes, 2014-07, Vol.89, p.53-57 版權： 2014 Elsevier Ltd 版權： Copyright © 2014 Elsevier Ltd. All rights reserved. 識別號： ISSN: 0969-8043 識別號： ISSN: 1872-9800 識別號： EISSN: 1872-9800 識別號： DOI: 10.1016/j.apradiso.2014.02.006 識別號： PMID: 24589448
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