Fiber optic particle plasmon resonance sensor based on plasmonic light scattering interrogation

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題名:	Fiber optic particle plasmon resonance sensor based on plasmonic light scattering interrogation
作者:	黃貞翰;Lin, H.-Y.;Huang, C.-H.;Chau, L.-K.
貢獻者:	生醫理工學院生醫科學與工程學系
關鍵詞:	Biochemistry;Detection;Fiber optic sensor;Fiber optics;high-throughput biochemical detection;nanoparticle;Optical fibers;particle plasmon resonance;plasmonic scattering;Plasmonics;Refractivity;Scattering;Sensors
日期:	2012-11-01
上傳時間:	2026-04-23 11:16:06 (UTC+8)
出版者:	Berlin: WILEY-VCH Verlag
摘要:	摘要： A highly sensitive fiber optic particle plasmon resonance sensor (FO‐PPR) is demonstrated for label‐free biochemical detection. The sensing strategy relies on interrogating the plasmonic scattering of light from gold nanoparticles on the optical fiber in response to the surrounding refractive index changes or molecular binding events. The refractive index resolution is estimated to be 3.8 × 10‐5 RIU. The limit of detection for anti‐DNP antibody spiked in buffer is 1.2 × 10‐9 g/ml (5.3 pM) by using the DNP‐functionalized FO‐PPR sensor. The image processing of simultaneously recorded plasmonic scattering photographs at different compartments of the sensor is also demonstrated. Results suggest that the compact sensor can perform multiple independent measurements simultaneously by means of monitoring the plasmonic scattering intensity via photodiodes or a CCD. The potential of using a combination of different kinds of noble metal nanoparticles with different types of functionalized probes in multiple cascaded detection windows on a single fiber to become an inexpensive and ultrasensitive linear‐array sensing platform for higher‐throughput biochemical detection is provided. A highly sensitive fiber optic particle plasmon resonance sensor (FO‐PPR) is demonstrated for label‐free biochemical detection. The sensing strategy relies on interrogating the plasmonic scattering of light from gold nanoparticles on the optical fiber in response to the surrounding refractive index changes or molecular binding events. 其他題名： Ann. Phys 出版者： Berlin: WILEY-VCH Verlag 出版日期： 2012-11 出處： Annalen der Physik, 2012-11, Vol.524 (11), p.705-712 資源來源： Wiley Online Journals ** 版權： Copyright © 2012 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim 版權： Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim 識別號： ISSN: 0003-3804 識別號： EISSN: 1521-3889 識別號： DOI: 10.1002/andp.201200157 識別號： CODEN: ANPYA2
顯示於類別:	[生醫科學與工程學系] 期刊論文

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