Intrinsic fluctuations of cell migration under different cellular densities

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题名:	Intrinsic fluctuations of cell migration under different cellular densities
作者:	黎璧賢;Chen, Song;Li, Na;Hsu, Su-Fan;Zhang, Jiazheng;Lai, Pik-Yin;Chan, Chi-Keung;Chen, Wei
贡献者:	理學院物理學系
关键词:	Agar;Algorithms;Amplitudes;Cellular;Density;Dictyostelium - physiology;Fluctuation;Kinetics;Linearity;Microscopy;Microscopy, Video;Migration;Movement
日期:	2014-05-21
上传时间:	2026-04-23 12:07:17 (UTC+8)
出版者:	Royal Society of Chemistry;England
摘要:	摘要： The motility of the Dictyostelium discoideum (DD) cell is studied by video microscopy when the cells are plated on top of an agar plate at different densities, n . It is found that the fluctuating kinetics of the cells can be divided into two normal directions: the cell's forward-moving direction and its normal direction. Along the forward-moving direction, the slope of the amplitude of fluctuation vs. velocity ( R \|\| ( v )) increases with n , while along the normal direction the slope of R is independent of n . Both R \|\| and R are functions of the cell speed v . The observed linearity in R ( v ) indicated that the amplitude of orientational fluctuation ( κ ) of DD cells is a constant independent of v . The independence of the slope of R ( v ) on n indicated that κ is also not affected by cellular interactions. The independence of κ on both v and n suggests that orientational fluctuation originates from the intrinsic property of motion fluctuations in DD. The motility of the Dictyostelium discoideum (DD) cell is studied by video microscopy when the cells are plated on top of an agar plate at different densities, n . 其他題名： Soft Matter 出版者： England 出版日期： 2014-05-21 出處： Soft matter, 2014-05, Vol.1 (19), p.3421-3425 識別號： ISSN: 1744-683X 識別號： ISSN: 1744-6848 識別號： EISSN: 1744-6848 識別號： DOI: 10.1039/c3sm52752b 識別號： PMID: 24643513
显示于类别:	[物理學系] 期刊論文

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