隨著高科技產業製程日益複雜，化學品種類與使用量持續增加，如何降低作業場所之化學品暴露風險已成為職業衛生管理之重要課題。然而，不同暴露評估方法於理論架構、輸入參數及判定邏輯上有所差異，可能導致相同暴露情境產生不同風險分級結果。 本研究以國內某 TFT-LCD 廠製程化學品為研究對象，篩選具職業暴露限值之化學品共 75 項，分別採用 CCB、SQRA、AIHA-SVP、TW-Quantitative Tool 及 ECETOC TRA v3.2 等五種暴露評估方法進行風險分級，並透過風險等級分布、模型判定特性、一致性及相關性分析，比較各方法之差異與產業適用性。 研究結果顯示五種暴露評估方法對風險判定具有明顯差異，整體一致性分析顯示 Kendall’s W 為 0.321（p < 0.001），代表五種暴露評估方法間達統計顯著但僅屬中度一致性；相關性分析顯示CCB 與 SQRA、TW-Quantitative Tool 與 ECETOC TRA v3.2 具有較高相關性，反映判定邏輯相近之方法，評估結果較為接近。綜合而言，五種暴露評估方法於 TFT-LCD 製程中具有不同之適用性，雖呈現部分共通趨勢，但無法相互替代。建議實務應用上應依評估目的選擇適當方法，以提升風險判定之合理性與管理效益。;As manufacturing processes in the high-tech industry become increasingly complex， along with the continuous increase in the variety and quantity of chemicals used， occupational chemical exposure risk assessment has become an important issue in occupational health management. However， different exposure assessment methods vary in their theoretical frameworks， input parameters， and decision-making logic， which may lead to different risk classification results under the same exposure scenario. This study focuses on process chemicals used in a TFT-LCD manufacturing plant in Taiwan. A total of 75 chemicals with established occupational exposure limits (OELs) were screened and evaluated using five exposure assessment methods including CCB， SQRA， AIHA-SVP， TW-Quantitative Tool， and ECETOC TRA v3.2. To compare the differences and industrial applicability of these methods， analyses were conducted on risk rating distributions， method-specific decision-making characteristics， concordance， and correlations. The results showed clear differences in risk determination among the five exposure assessment methods. The overall concordance analysis yielded a Kendall’s W of 0.321 (p < 0.001)， indicating statistically significant but only moderate agreement among the five methods. Correlation analysis further revealed higher correlations between CCB and SQRA， as well as between the TW-Quantitative Tool and ECETOC TRA v3.2， suggesting that methods with similar decision-making logic tend to produce more similar assessment outcomes. Overall， the five exposure assessment methods have distinct applicability profiles in TFT-LCD manufacturing processes. Although they exhibit certain common trends， they are not mutually interchangeable. Therefore， in practical applications， appropriate methods should be selected according to the assessment objectives to improve the rationality of risk determination and the effectiveness of risk management.
