Physical properties of a porcine internal thoracic artery fixed with an epoxy compound

NCUIR > Engineering College > National Central University Department of Chemical & Materials Engineering > journal & Dissertation > Item 987654321/26614

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Title:	Physical properties of a porcine internal thoracic artery fixed with an epoxy compound
Authors:	Sung,HW;Hsu,CS;Lee,YS
Contributors:	化學工程與材料工程學系
Keywords:	DERMAL SHEEP COLLAGEN;IN-VITRO DEGRADATION;VASCULAR PROSTHESES;GLUTARALDEHYDE;REVASCULARIZATION;BIOMATERIALS;EXPERIENCE;FIXATION;TISSUES;GRAFTS
Date:	1996
Issue Date:	2010-06-29 17:32:24 (UTC+8)
Publisher:	中央大學
Abstract:	This study aimed to investigate the physical properties of a porcine internal thoracic artery fixed with an epoxy compound. Fresh and glutaraldehyde-fixed porcine arteries were used as controls. Both the epoxy-fixed and glutaraldehyde-fixed porcine arteries showed significant increases in fixation index and denaturation temperature as compared to the fresh one. Additionally, the resistance of porcine arteries against bacterial collagenase in vitro degradation increased significantly after cross-linking with the epoxy compound or glutaraldehyde. The reduction of the tensile strength of the epoxy-fixed artery after bacterial collagenase degradation was more severe than in its glutaraldehyde-fixed counterpart. Generally, with increasing pH, temperature or fixative concentration, the fixation indices and denaturation temperatures of the epoxy-fixed porcine arteries increased. The results obtained in this study may be used to optimize the fixation process for developing a small-diameter biological vascular graft fixed by an epoxy compound. (C) 1996 Elsevier Science Limited
Relation:	BIOMATERIALS
Appears in Collections:	[National Central University Department of Chemical & Materials Engineering] journal & Dissertation

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