Rational design and synthesis of unsaturated 2,5-dioxopiperazine derivatives as potential protein tyrosine kinase inhibitors

Please use this identifier to cite or link to this item: http://ir.lib.ncu.edu.tw/handle/987654321/28388

Title:	Rational design and synthesis of unsaturated 2,5-dioxopiperazine derivatives as potential protein tyrosine kinase inhibitors
Authors:	Li,WR;Peng,SZ
Contributors:	中央大學
Keywords:	SOLID-PHASE SYNTHESIS;PEPTIDE-SYNTHESIS;RACEMIZATION;METHYLATION;ACIDS
Date:	1998
Issue Date:	2010-06-29 19:47:44 (UTC+8)
Publisher:	化學研究所
Abstract:	The first general method for the synthesis of a library of trifunctionalized (Z)-3-alkylidene-2,5-piperazinediones as potential protein tyrosine kinase inhibitors from commercially available amino compounds, alpha-keto acids and aldehydes using a novel cyclization/cleavage strategy on solid support is described. (C) 1998 Published by Elsevier Science Ltd. All rights reserved.
Relation:	TETRAHEDRON LETTERS
Appears in Collections:	[Graduate Institute of Chemistry] journal & Dissertation

Files in This Item:

File	Description	Size	Format
index.html		0Kb	HTML	534	View/Open

社群 sharing