On the possible origin of bulk third harmonic generation in skin cells

Please use this identifier to cite or link to this item: http://ir.lib.ncu.edu.tw/handle/987654321/51046

Title:	On the possible origin of bulk third harmonic generation in skin cells
Authors:	Su,TY;Liao,CS;Yang,CY;Zhuo,GY;Chen,SY;Chu,SW
Contributors:	光電科學與工程學系
Keywords:	3RD-HARMONIC GENERATION;LIGHT-SCATTERING;MICROSCOPY;MELANIN
Date:	2011
Issue Date:	2012-03-27 18:16:39 (UTC+8)
Publisher:	國立中央大學
Abstract:	We studied third harmonic generation (THG) of melanin solution with concentrations similar to melanocytes in human skin. In contrast to conventional observation of THG at interface, bulk THG was detected inside the solution due to the formation of melanin hydrocolloids. A linear relationship between melanin concentration and THG intensity was found, suggesting THG originated from high-order hyper-Rayleigh scattering. By fitting this linear relationship, third-order hyperpolarizability of melanin hydrocolloids was determined to be three orders larger than that of water. Our result will be useful for interpretation of THG signals in skin and other tissues containing colloidal particles. (C) 2011 American Institute of Physics. [doi:10.1063/1.3638458]
Relation:	APPLIED PHYSICS LETTERS
Appears in Collections:	[Department of Optics and Photonics] journal & Dissertation

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