探討牛樟芝CCM111對細胞訊息傳遞之影響;The Study of CCM111 in Cell Signaling Transduction Pathways

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Title:	探討牛樟芝CCM111對細胞訊息傳遞之影響;The Study of CCM111 in Cell Signaling Transduction Pathways
Authors:	林婷婷;Lin,Ting-Ting
Contributors:	系統生物與生物資訊研究所
Keywords:	發炎反應;中草藥;牛樟芝;訊息傳遞;inflammation;signaling transduction pathway;Antrodia camphorate;Traditional chinese medicine
Date:	2012-08-24
Issue Date:	2012-09-11 18:40:22 (UTC+8)
Publisher:	國立中央大學
Abstract:	牛樟芝，是台灣菌類特有種。一直以來被台灣原住民作為解酒以及治療肝病的中草藥。有研究報導指出，牛樟芝萃取物具有抗肝炎病毒的效果並且能夠抑制肝癌的形成。訊息傳遞控制了細胞的功能，如細胞增生、分化等。而我們知道，許多癌症的產生與訊息傳遞的異常表現有關係。因此欲建立訊息傳遞平台，進行對牛樟芝的全面性篩選，進而得知牛樟芝能透過調控哪一條訊息傳遞而達到抗發炎反應甚至抗腫瘤生長的功能，為我實驗的主要目的。 CCM111, an extraction of Antrodia camphorate (AC) is a genus of fungi in Taiwan. It is well known as a Traditional Chinese Medicine (TCM) and has been widely used during Taiwanese aborigines as a drug for treating hangover and liver diseases. In my study, we have collected stable cell lines expressing transcriptional regulatory elements in front of luciferase reporter to monitor activity of the signaling pathways.
Appears in Collections:	[Institute of Systems Biology and Bioinformatics] Electronic Thesis & Dissertation

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