探討量子光照射老鼠視網膜色素上皮細胞的影響;Discussing the impact of quantum light irradiation on retinal pigment epithelial cells in mice

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题名:	探討量子光照射老鼠視網膜色素上皮細胞的影響;Discussing the impact of quantum light irradiation on retinal pigment epithelial cells in mice
作者:	李欣燁;LEE, HSIN-YEH
贡献者:	光電科學與工程學系
关键词:	量子光學;量子相干性;醫療檢測;quantum optics;quantum coherence;medical testing
日期:	2024-07-18
上传时间:	2024-10-09 15:37:29 (UTC+8)
出版者:	國立中央大學
摘要:	隨著AI和量子科學的蓬勃發展，許多醫療的檢測都朝向精準醫學的目標而努力，本研究的目的是探討量子光學對人體視神經檢測的可行性。我們利用白老鼠視網膜色素上皮細胞來模擬。本論文設定量測的模擬條件包括：波長為1560nm的紅外光雷射、老鼠視網膜上皮細胞的折射率為1.353，並將樣品細胞分成四組，分別為母老鼠的左眼、右眼、公老鼠的右眼、子老鼠的右眼，樣品的截面直徑為10µm，厚度為0.8µm，通過Python模擬量子光學SPDC的過程，我們模擬10到50個光子數目照射老鼠視網膜上皮細胞，分別量測活體細胞、死亡細胞，並先在S路徑上只放母細胞左眼，經S與I路徑干涉後的數據做為對照組，再比較四組細胞試片分別放在S路徑上串聯或者放在S路徑與I路徑上並聯方式放置試片，所得到每一組相干性的結果與對照組比對相干性的差異程度，來觀察量子光量測用於細胞的鑑別度的可靠性。;With the booming development of AI and quantum science, many medical tests are striving towards the goal of precision medicine. The purpose of this study is to explore the feasibility of quantum optics for human optic nerve detection. We simulate using the retinal pigment epithelial cells of white mice. The simulated conditions set in this paper include: an infrared laser with a wavelength of 1560nm, the refractive index of the mouse’s retinal epithelial cells is 1.353, and the sample cells are divided into four groups, namely the left eye of the mother mouse, the right eye, the right eye of the male mouse, and the right eye of the child mouse. The cross-sectional diameter of the sample is 10 microns, the thickness is 0.8 microns, and the process of quantum optics SPDC is simulated through Python. We simulate the irradiation of 10 to 50 photons on the retinal epithelial cells of mice, measure live cells and dead cells respectively, and first put only the left eye of the mother cell on the S path, and the data after the interference of the S and I path is used as the control group. Then compare the coherence results obtained from each group of cell samples placed in series on the S path or placed in parallel on the S and I path and compare the degree of coherence difference with the control group to observe the reliability of quantum light measurement for cell discrimination.
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