中大學術數位典藏-NCU Institutional Repository:Item 987654321/102846
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    题名: Novel application of a multiscale entropy index as a sensitive tool for detecting subtle vascular abnormalities in the aged and diabetic
    作者: 羅孟宗;Wu, Hsien-Tsai;Lo, Men-Tzung;Chen, Guan-Hong;Sun, Cheuk-Kwan;Chen, Jian-Jung
    贡献者: 生醫理工學院生醫科學與工程學系
    关键词: Adult;Aged;Aged, 80 and over;Aging;Algorithms;Anthropometry;Blood Pressure;Blood Vessels - pathology;Case-Control Studies;Diabetes Mellitus - diagnosis;Entropy;Female;Glycated Hemoglobin A - chemistry;Hemodynamics;Humans;Lipids - chemistry;Male;Middle Aged;Models, Statistical;Monitoring, Physiologic - instrumentation;Monitoring, Physiologic - methods;Reproducibility of Results;Young Adult
    日期: 2013-03-15
    上传时间: 2026-04-23 11:17:59 (UTC+8)
    出版者: Hindawi Publishing Corporation;Cairo, Egypt: Hindawi Puplishing Corporation
    摘要: 摘要: Although previous studies have shown the successful use of pressure-induced reactive hyperemia as a tool for the assessment of endothelial function, its sensitivity remains questionable. This study aims to investigate the feasibility and sensitivity of a novel multiscale entropy index (MEI) in detecting subtle vascular abnormalities in healthy and diabetic subjects. Basic anthropometric and hemodynamic parameters, serum lipid profiles, and glycosylated hemoglobin levels were recorded. Arterial pulse wave signals were acquired from the wrist with an air pressure sensing system (APSS), followed by MEI and dilatation index (DI) analyses. MEI succeeded in detecting significant differences among the four groups of subjects: healthy young individuals, healthy middle-aged or elderly individuals, well-controlled diabetic individuals, and poorly controlled diabetic individuals. A reduction in multiscale entropy reflected age- and diabetes-related vascular changes and may serve as a more sensitive indicator of subtle vascular abnormalities compared with DI in the setting of diabetes.
    其他題名: Comput Math Methods Med
    出版者: Cairo, Egypt: Hindawi Puplishing Corporation
    出版日期: 2013-01-01
    出處: Computational and mathematical methods in medicine, 2013-01, Vol.2013 (2013), p.1-8
    資源來源: EBSCOhost Academic Search Premier
    版權: Copyright © 2013 Hsien-Tsai Wu et al.
    版權: Copyright © 2013 Hsien-Tsai Wu et al. 2013
    識別號: ISSN: 1748-670X
    識別號: ISSN: 1748-6718
    識別號: EISSN: 1748-6718
    識別號: DOI: 10.1155/2013/645702
    識別號: PMID: 23509600
    显示于类别:[生醫科學與工程學系] 期刊論文

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