Novel application of a multiscale entropy index as a sensitive tool for detecting subtle vascular abnormalities in the aged and diabetic

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題名:	Novel application of a multiscale entropy index as a sensitive tool for detecting subtle vascular abnormalities in the aged and diabetic
作者:	羅孟宗;Wu, Hsien-Tsai;Lo, Men-Tzung;Chen, Guan-Hong;Sun, Cheuk-Kwan;Chen, Jian-Jung
貢獻者:	生醫理工學院生醫科學與工程學系
關鍵詞:	Adult;Aged;Aged, 80 and over;Aging;Algorithms;Anthropometry;Blood Pressure;Blood Vessels - pathology;Case-Control Studies;Diabetes Mellitus - diagnosis;Entropy;Female;Glycated Hemoglobin A - chemistry;Hemodynamics;Humans;Lipids - chemistry;Male;Middle Aged;Models, Statistical;Monitoring, Physiologic - instrumentation;Monitoring, Physiologic - methods;Reproducibility of Results;Young Adult
日期:	2013-03-15
上傳時間:	2026-04-23 11:17:59 (UTC+8)
出版者:	Hindawi Publishing Corporation;Cairo, Egypt: Hindawi Puplishing Corporation
摘要:	摘要： Although previous studies have shown the successful use of pressure-induced reactive hyperemia as a tool for the assessment of endothelial function, its sensitivity remains questionable. This study aims to investigate the feasibility and sensitivity of a novel multiscale entropy index (MEI) in detecting subtle vascular abnormalities in healthy and diabetic subjects. Basic anthropometric and hemodynamic parameters, serum lipid profiles, and glycosylated hemoglobin levels were recorded. Arterial pulse wave signals were acquired from the wrist with an air pressure sensing system (APSS), followed by MEI and dilatation index (DI) analyses. MEI succeeded in detecting significant differences among the four groups of subjects: healthy young individuals, healthy middle-aged or elderly individuals, well-controlled diabetic individuals, and poorly controlled diabetic individuals. A reduction in multiscale entropy reflected age- and diabetes-related vascular changes and may serve as a more sensitive indicator of subtle vascular abnormalities compared with DI in the setting of diabetes. 其他題名： Comput Math Methods Med 出版者： Cairo, Egypt: Hindawi Puplishing Corporation 出版日期： 2013-01-01 出處： Computational and mathematical methods in medicine, 2013-01, Vol.2013 (2013), p.1-8 資源來源： EBSCOhost Academic Search Premier 版權： Copyright © 2013 Hsien-Tsai Wu et al. 版權： Copyright © 2013 Hsien-Tsai Wu et al. 2013 識別號： ISSN: 1748-670X 識別號： ISSN: 1748-6718 識別號： EISSN: 1748-6718 識別號： DOI: 10.1155/2013/645702 識別號： PMID: 23509600
顯示於類別:	[生醫科學與工程學系] 期刊論文

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